Endocrine Abstracts

Objective: To report a rare cause of ectopic adrenocorticotropic hormone (ACTH) secretion leading to Cushing syndrome.Methods: We describe the clinical presentation and management of a case of Cushing syndrome attributable to ectopic ACTH secretion from small cell cancer of the prostate.Results: In a 74-year-old man developed hypocalemia and heart failure. He was found to have severe hypokalemia (serum potassium, 2.37 mEq/l). Hormo...

Primary adrenal lymphoma(PAL) is very rare and constitutes <1% of cases of extranodal lymphomas. Most common subtype of PAL is diffuse large B cell lymphoma. A 46-year-old male patient without any underlying disease was admitted to our hospital with a complaint of bilateral back pain, cough and fever. His laboratory tests revealed a hemoglobin: 5 g/dl (14–17.5), white blood cell: 3.8 103/µl (4.4–11.3), platelet: 111 103/µl (130&#...

Objective: Thyroid hormones are powerful mediators of numerous physiological and metabolic processes, including blood clotting, and thyroid dysfunction can adversely affect various stages in the coagulation cascade. Mean platelet volume (MPV) is used to measure platelet size and may indicate platelet activity. Studies have reported that increased MPV is associated with atherosclerotic lesions and cardiovascular diseases, and conflicting results have been reported for the relat...

Diabetes caused by immune checkpoint inhibitors is extremely rare. A 48-year-old male patient with a diagnosis of squamous cell cancer in the external auditory canal and operated on received adjuvant radiotherapy. When relapse was seen, 6 cycles of 5-fluorouracil, carboplatin, and cetuximab were administered. The patient was admitted to the hospital with nausea, vomiting, and abdominal pain 10 days after the second cycle infusion, when pembrolizumab was started when the crania...

Both pituitary and adrenal gland metastases of lung cancer are very rare. A 79-year-old male patient with diabetes mellitus and hypertension was admitted to our hospital because of a mass in the lungs of the thorax CT. TSH: <0.005 UIU/ml (0.27–4.2), free T4: 0.794 ng/dl (0.93–1.7). Other pituitary hormones were also examined: FSH: 0.708 mIU/ml (1.5–12.4), LH: <0.1 mIU/ml (1.7–8.6), prolactin: 12.7 ng/ml (4.04–15.2), total testosterone: &#6...

Pituitary adenomas are the most common cause of pituitary lesions. Atypical teratoid rhabdoid tumors are rare aggressive tumors of the central nervous system and are generally seen in children younger than 2 years of age, but also rarely in adults. Only 18 cases have been reported with pituitary involvement to 2018. Median survival in these tumors in adults is 21 months and the cause of death is usually tumor recurrence or leptomeningeal spread. Although surgery, chemotherapy ...

Introduction: Granulomatosis with polyangiitis (GPA) is a systemic vasculitis with necrotizing granulomatous inflammation. Any organ including the pituitary can be involved. Here we report a patient diagnosed with GPA who had nearly complete resolution of pituitary mass after cyclophosphamide and methylprednisolone treatment.Case46 year old female patient was admitted to the hospital after being examined by several departments for ...

Multiple endocrine neoplasia type 1 is a rare autosomal-dominant disorder. The most common endocrine tumors are parathyroid tumors, which cause hyperparathyroidism and hypercalcemia. Other tumors of MEN 1 include pituitary tumors for example prolactinomas and enteropancreatic tumors such as gastrinomas, insulinomas, VIPomas, carcinoid tumors. We report a case of a 31 year old male with MEN 1 presenting hypercalcemia with complaints of fatigue and weakness. On further questioni...